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Semin Med Pract 
2002 Sep;5(3):6-16
Applying evidence to the care of a patient with hepatitis C: how to develop a focused clinical question
Muir AJ, Schardt CM, Keitz SA

Evidence-based medicine (EBM) is regarded as an essential skill for physicians and a fundamental competency to be demonstrated by residents. Applying best evidence to patient care can be challenging, but by using a systematic approach, physicians can develop and maintain the essential skills of evidence-based practice. This article initiates a new journal feature devoted to examining the specific skills needed to apply current best evidence to clinical decisions. The authors use an actual patient case from their practice to illustrate a five-step EBM approach, with emphasis on how to develop a focused clinical question. As the authors note, for any given case, numerous questions may arise. Deciding which questions to pursue and determining how best to find the answers are essential skills.

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