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Semin Med Pract 
2002 Dec;5(4):5-12
Applying evidence in the diagnosis of a patient with shortness of breath: how to evaluate a new diagnostic test
Adler RS, Korenstein D, Goldstein C, McGinn TG

Diagnostic tests are continuously evolving through the expansion of technology, challenging physicians to evaluate the usefulness of new tests when applying them to patient care. This article uses a patient scenario as the basis for examining how to obtain and incorporate available medical evidence when faced with a diagnostic dilemma. The authors examine several evidence-based medicine concepts, including how to estimate pretest probabilities for diagnosis, how to critically appraise a published study about a new diagnostic test, and how to use likelihood ratios when applying diagnostic tests to individual patients.

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