The patient may have carcinoma of the penis. Biopsy of the lesion is
necessary before initiation of therapy. No harmful effects have been
associated with tumor dissemination secondary to biopsy. The majority
of penile tumors are squamous cell carcinomas, which demonstrate
keratinization, epithelial pearl formation and various degrees of
mitotic activity. Radiation therapy may be considered in a select
group of patients after the diagnosis of penile cancer is established.
Topical antibiotic therapy is appropriate if the possibility of penile
cancer has been excluded. Topical chemotherapy with 5-fluorouracil is an
appropriate treatment for superficial premalignant lesions.
- Biopsy of the penile lesion.
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Seminars in Medical Practice
Hospital Physician Board Review Manuals
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