Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Self-Assessment Questions


Answer 2

Figure 2

  1. Temporal artery biopsy. Given this patient’s high probability of having GCA, there is no need for a fundoscopic examination or a 2-dimensional Doppler echocardiogram. Several available modalities may help establish the diagnosis, including temporal artery ultrasound, CT, positron emission tomography, magnetic resonance imaging, and angiographic studies. However, the gold standard for diagnosing GCA remains a temporal artery biopsy demonstrating granulomatous inflammation with intimal hyperplasia and central narrowing (Figure 2).1 A temporal artery biopsy will still show histologic changes after corticosteroids have been administered (7-14 days), but radiologic findings may change.

    1. Klein RG, Hunder GC, Stanson AW, Shep SG. Large artery involvement in giant cell (temporal) arteritis. Ann Intern Med 1975;83:806-12.

Click here to return to the questions


Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 5/23/08 • nvf