Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Self-Assessment Questions


Answer 6
  1. Hands and knees. Although it seems intuitively clear that weight-bearing joints are affected by obesity, in reality, only the knees are significantly affected. Epidemiologic studies have shown that osteoarthritis of the hand is also increased in the context of obesity, a finding that has led researchers to hypothesize a circulating factor as a causative agent. Because increased body fat can result in increased conversion of precursor hormones to active estrogen compounds, an estrogen-like compound is a possible causative agent for osteoarthritis in obese patients.

Click here to return to the questions


Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 1/04/08 • kkj