Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Interactive:
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Quiz
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Exams
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Self-Assessment Questions

Pulmonary Disease


Answer 2
  1. LDH. Traditionally, Light’s criteria have been used to differentiate transudative from exudative effusions. These criteria include: (1) pleural fluid protein to serum protein ratio greater than 0.5, (2) pleural fluid LDH to serum LDH ratio greater than 0.6, and (3) pleural fluid LDH ratio greater than two thirds the upper limit of normal for the serum LDH. Exudative effusions meet at least 1 of Light’s criteria, and transudates meet none. Recently, several other tests have been proposed as well. A pleural fluid cholesterol concentration greater than 60 mg/dL and a pleural fluid to serum albumin gradient of less than 1.2 may also suggest an exudative effusion.2 Pleural fluid glucose, pH, and cell count levels are helpful in characterizing pleural effusions but do not differentiate between transudates and exudates.

    REFERENCES
    2. Light RW. Pleural diseases. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2001:44-45, 57-8, 163-5.

Click here to return to the questions

 

Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 1/04/08 • kkj