Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Self-Assessment Questions

Pulmonary Disease

Answer 2
  1. Sweat glands. Most CF patients have 3 distinct abnormal characteristics. First, the ducts of the mucus-secreting glands are obstructed due to an increase in viscosity of these secretions leading to glandular dilatation and destruction. Second, CF patients are prone to chronic bacterial colonization and infections. Third, the sweat glands are not obstructed in CF patients because in serous glands such as sweat glands there are abnormal concentrations of inorganic ions, rather than glandular obstruction with thick mucus. The quantitative pilocarpine iontophoresis sweat test is a uniformly accepted method for diagnosing CF. The sweat gland ducts must be patent for this test. Obstruction of airways leads to bronchiectasis and atelectasis; pancreatic duct obstruction leads to pancreatitis and malabsorption; and plugging of bile ducts leads to obstructive jaundice.

Click here to return to the questions


Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 1/04/08 • kkj