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Self-Assessment Questions

Pulmonary Disease

Answer 3
  1. Start 4 antituberculous medications. The patient has a history and supporting data consistent with active pulmonary tuberculosis (TB) and HIV infection, both of which must be treated. The concomitant treatment of both diseases has produced paradoxical reactions; by delaying highly active antiretroviral therapy (HAART) for at least 2 months, these reactions can be avoided while simultaneously avoiding the drug interactions associated with the rifamycins, which are used to treat TB, and HAART.4

    4. Burman WJ, Jones BE. Treatment of HIV-related tuberculosis in the era of effective antiretroviral therapy. Am J Respir Crit Care Med 2001;164:7-12.

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