Bupropion is effective for the treatment of adult ADHD.5 In an 8-week, multisite, placebo-controlled study of 162 adults with ADHD, more patients responded to bupropion XL than placebo by week 8 (53% versus 31%; P = 0.004), with a significantly greater proportion of patients responding as early as week 2 (P = 0.01).6 Alprazolam is a benzodiazepine used in the treatment of anxiety disorders, panic disorders, and depression-related anxiety. Lithium is used to treat manic episodes of manic-depressive illness, and quetiapine is an atypical antipsychotic agent used to treat bipolar disorder.
5. Wilens TE, Spencer TJ, Biederman J, et al. A controlled clinical trial of bupropion for attention deficit hyperactivity disorder in adults. Am J Psychiatry 2001;158:282–8.
6. Wilens TE, Haight BR, Horrigan JP, et al. Bupropion XL in adults with
attention-deficit/hyperactivity disorder: a randomized, placebo-controlled study. Biol Psychiatry 2005;57:793–801.
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