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Answer 5
  1. Evaluation for depression. Studies suggest that 18% to 40% of patients with Parkinson’s disease may also experience major depression or dysthymic disorder.8 Symptoms of depression and Parkinson’s disease are similar,2 which can make the diagnosis of depression more difficult. Therefore, patients with Parkinson’s disease should be carefully evaluated for comorbid depression. The Hamilton Depression Inventory is a valid tool for evaluating depression in patients with Parkinson’s disease9 and could be used to assist clinicians with this process. Chest radiograph, prolactin level, and urine protein electrophoresis are not indicated for the routine evaluation of Parkinson’s disease.

    2. Schrag A, Barone P, Brown RG, et al. Depression rating scales in Parkinson’s disease: critique and recommendations. Mov Disord 2007;22:1077-92.

    8.  Cummings JL. Depression and Parkinson’s disease: a review. Am J Psychiatry 1992;149:443-54.

    9. Dissanayaka NN, Sellbach A, Matheson S, et al. Validity of Hamilton Depression Inventory in Parkinson’s disease. Mov Disord 2007;22:399-403.

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