Studies suggest that 18% to 40% of patients with Parkinsons disease may also experience major depression or dysthymic disorder.8 Symptoms of depression and Parkinsons disease are similar,2 which can make the diagnosis of depression more difficult. Therefore, patients with Parkinsons disease should be carefully evaluated for comorbid depression. The Hamilton Depression Inventory is a valid tool for evaluating depression in patients with Parkinsons disease9 and could be used to assist clinicians with this process. Chest radiograph, prolactin level, and urine protein electrophoresis are not indicated for the routine evaluation of Parkinsons disease.
- Evaluation for depression.
2. Schrag A, Barone P, Brown RG, et al. Depression rating scales in Parkinsons disease: critique and recommendations. Mov Disord 2007;22:1077-92.
8. Cummings JL. Depression and Parkinsons disease: a review. Am J Psychiatry 1992;149:443-54.
9. Dissanayaka NN, Sellbach A, Matheson S, et al. Validity of Hamilton Depression Inventory in Parkinsons disease. Mov Disord 2007;22:399-403.
Click here to return to the questions
Seminars in Medical Practice
Hospital Physician Board Review Manuals
Copyright © 2009, Turner White Communications
Updated 1/31/08 kkj