Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Interactive:
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Quiz
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Exams
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Self-Assessment Questions

Orthopaedic Surgery


Answer 2
  1. Wide resection and chemotherapy. Successful surgical management of osteosarcoma is achieved by obtaining wide surgical margins with limb-sparing resection. However, the presence of metastasis is the largest predictor of 5-year survival, with a 10% to 20% rate compared with 60% to 80% without evidence of metastasis.1 Preoperative and postoperative chemotherapy significantly improve outcomes for patients with osteosarcoma. Above the knee amputation is an option, but limb salvage is indicated in patients with resectable tumors. Curettage and bone grafting and wide resection alone are insufficient for tumor excision. Radiation is not as effective in tumor eradication as compared with chemotherapy.

    REFERENCE
    1.
     Gibbs CP Jr, Weber K, Scarborough MT. Malignant bone tumors. Instr Course Lect 2002;51:413-28.

Click here to return to the questions

 

Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 3/20/08 • nvf