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Answer 3
  1. Mantle cell lymphoma. This patient has lymphomatous polyposis (not to be confused with lymphomatoid polyposis) associated with mantle cell lymphoma. For reasons that are unclear, the disease has a predilection for the intestinal tract. Mantle cell lymphoma is a progressive disease that results in death within an average of 3 to 5 years despite aggressive treatment regimens, including stem cell transplantation.4 Burkitt’s lymphoma often presents as a lymph node mass near the cecum in young men but is generally a rapidly growing malignancy that causes symptoms such as night sweats, weight loss, and abdominal pain. Diffuse large B-cell lymphoma, follicular lymphoma, and marginal zone lymphoma rarely present as multiple colonic polyps.

    4. Bertoni F, Zucca E, Cavalli F. Mantle cell lymphoma. Curr Opin Hematol 2004;11:411-8.

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