Opioid-induced constipation; institute daily bowel regimen.
Constipation is the most common opioid side effect. Because tolerance to the opioid-induced constipation does not develop, prevention with stool softeners and laxatives is necessary. Opioid-induced peristaltic slowing can mimic or worsen symptoms of intestinal obstruction and other pathologies. A plain abdominal radiograph may be needed to make the differential diagnosis.