This patient has classic signs and symptoms of hypercalcemia and should be managed with hydration (approximately 6 L/day). Bisphosphonates should be started early, but it will take several days for their full effect to be achieved. In addition to hydration, calcitonin can be added to control a high calcium level within the first 2 to 3 days. Loop diuretics should not be used until the patient is adequately hydrated.