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Obstetrics & Gynecology


Answer 5
  1. Weight gain. Weight gain has been absolved as an adverse effect of HRT. The Rancho Bernardo and Postmenopausal Estrogen/Progestogen Intervention studies found no significant weight difference between women who did and did not use hormones. Uterine bleeding, abdominal bloating, breast tenderness, weight gain, and fluid retention in extremities are common adverse effects of HRT, which can decrease patient compliance and lead to discontinuance of therapy.

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