Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map

Self-Assessment Questions


Multiple Sclerosis: Review Questions

Gokhan L. Akfirat, MD

Dr. Akfirat is an Instructor of Neurology, New York Medical College, Metropolitan Hospital, New York, NY.

Choose the single best answer for each question.

1. Which of the following statements regarding multiple sclerosis (MS) is NOT correct?
  1. MS is an immune-mediated disease
  2. MS is the most common neurologic disorder affecting young adults
  3. The male-to-female ratio in persons affected by MS is 2:1
  4. The risk for MS in a monozygotic twin is 25% to 30%
  5. The risk for MS in the general population is 0.1%
Click here to compare your answer.

2. A 31-year-old woman with a history of MS, including 2 exacerbations with complete recovery in the past 2 years, develops optic neuritis. She is treated with methylprednisolone sodium succinate, intravenously, and experiences complete resolution of her symptoms in 3 weeks. Which of the following types of MS does the patient most likely have?

  1. Primary progressive
  2. Progressive-relapsing
  3. Relapsing-remitting
  4. Secondary progressive
Click here to compare your answer.

3. Which of the following is associated with a better prognosis in a patient with MS?

  1. Brainstem and cerebellar symptoms
  2. Disease onset after age 35 years
  3. Female gender
  4. Higher incidence of attacks
  5. Poor recovery after an exacerbation
Click here to compare your answer.

4. Which of the following agents is NOT typically used to manage fatigue in patients with MS?
  1. Amantadine
  2. Baclofen
  3. Fluoxetine
  4. Methylphenidate
  5. Pemoline
Click here to compare your answer.

5. Which of the following statements regarding cognitive function in patients with MS is NOT correct?

  1. Cognitive dysfunction has no association with disruption of daily activities in most patients with MS
  2. Cognitive dysfunction is related to brain atrophy and total lesion burden as seen on magnetic resonance imaging
  3. Cognitive dysfunction observed in patients with MS includes but is not limited to memory loss, inattention, slow information processing, and difficulty with abstract concepts
  4. Cognitive function is affected in approximately 45% to 60% of patients with MS
  5. Demyelination in the frontal lobes and corpus callosum is more often associated with cognitive dysfunction than is demyelination in other parts of the brain
Click here to compare your answer.

Self-Assessment Questions Main Page Top

Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 1/04/08 • kkj