Neurology Movement Disorders: Review Questions Donald S. Higgins, Jr., MD Dr. Higgins is an Associate Professor, Center for Neuropharmacology and Neuroscience and Department of Neurology, Albany Medical College, Albany, NY; and a member of the Hospital Physician Editorial Board. Choose the single best answer for each question.
	1. The primary neurochemical disturbance in idiopathic Parkinson’s disease involves which of the following neurotransmitters? Gamma-aminobutyric acid Dopamine Glutamate Serotonin Click here to compare your answer. 2. Which of the following pathologic abnormalities are characteristically found in patients with Parkinson’s disease? Corpora amylacea Lewy bodies Neurofibrillary tangles Pick bodies Click here to compare your answer. 3. Parkinson’s disease is characterized by each of the following clinical symptoms EXCEPT: Action tremor Bradykinesia Postural instability Resting tremor Click here to compare your answer. 4. Which of the following symptoms or symptom complexes must be present to diagnose Tourette’s syndrome? Coprolalia Multiple motor tics present for 6 months Multiple motor and phonic tics present for 12 months Vocal tics present for 3 months Click here to compare your answer.		5. What is the genetic inheritance pattern of Huntington’s disease? Autosomal dominant Autosomal recessive Maternal X-linked Click here to compare your answer. 6. What is the gene mutation present in Huntington’s disease? Frameshift mutation Mitochondrial DNA deletion Nuclear point mutation Trinucleotide repeat expansion Click here to compare your answer. 7. Which of the following is the most common tardive, drug-induced movement disorder? Chorea Myoclonus Orolingual dyskinesia Tremor Click here to compare your answer.
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