Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Self-Assessment Questions


Answer 2
  1. Methyldopa. Antihypertensive therapy is essential to the treatment of preeclampsia. Methyldopa is the most commonly used antihypertensive agent in this setting, and randomized trials have demonstrated its long-term safety in children whose mothers were treated with this agent during pregnancy. Angiotensin-converting enzyme inhibitors are contraindicated in pregnancy and have been associated with oligohydramnios, neonatal renal failure, and death. IV magnesium sulfate is an accepted treatment for the prevention of eclamptic convulsions, and although it may slightly lower systemic blood pressure, it is not an effective antihypertensive agent. The use of diuretics to treat hypertension remains controversial. There are times when use of diuretics is essential, but they should not be used as first-line treatment of hypertension.

Click here to return to the questions


Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 1/04/08 • kkj