Antiviral therapy with oral valacyclovir, acyclovir, or famciclovir is beneficial when given within 48 hours of rash onset. Hospitalization for intravenous acyclovir is typically limited to complications of chickenpox, such as varicella pneumonia or encephalitis, or for immunosuppressed patients with chickenpox. Approximately 0.4% to 2.0% of pregnant women with chickenpox have infants with congenital varicella syndrome (ie, low birthweight, cutaneous scarring, limb hypoplasia, microcephaly, cortical atrophy, chorioretinitis, cataracts, and other abnormalities).
- Oral therapy with valacyclovir would be effective in reducing severity and duration of symptoms.
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