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Self-Assessment Questions

Internal Medicine

Clostridium difficile Colitis: Review Questions

Mark A. Marinella, MD, FACP, FACN, CNSP

Dr. Marinella is an assistant clinical professor, Department of Internal Medicine,
Wright State University School of Medicine, Dayton, OH.



Choose the single best answer for each question.

1. Which of the following is a morphologic description of Clostridium difficile colitis?
  1. Gram-negative bacillus
  2. Hydralazine
  3. Gram-positive bacillus
  4. Gram-negative coccus
  5. Gram-positive coccus
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2. All of the following statements regarding C. difficile colitis are correct EXCEPT

  1. Chemotherapeutic drugs may cause C. difficile colitis
  2. Constipation excludes this diagnosis
  3. Ileus can occur with severe illness
  4. Most cases result from recent antibiotic use
  5. Severe disease can lead to toxic megacolon
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  3. All of the following laboratory findings may be associated with C. difficile colitis EXCEPT
  1. Anemia
  2. Hypoalbuminemia
  3. Hypermagnesemia
  4. Hypokalemia
  5. Significant leukocytosis
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4. All of the following are treatment regimens for C. difficile colitis EXCEPT

  1. Oral metronidazole
  2. Oral vancomycin
  3. Intravenous metronidazole
  4. Intravenous vancomycin
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