Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Interactive:
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Quiz
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Exams
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Self-Assessment Questions

Geriatric Medicine


Answer 1
  1. Adverse drug reactions in older adults appear unrelated to the number of medications taken. Geriatric patients consume a disproportionate number of medications, compared with the rest of the US population. Polypharmacy, the use of multiple prescribed and over-the-counter medications and nutritional supplements, is a cause of adverse drug reactions. The chronic use of 2 medications simultaneously is associated with a 15% risk for adverse drug reaction, but the use of 5 drugs results in a risk of over 50%. Rather than age, the number of medications taken appears related to adverse effects in older adults. Institutionalized geriatric residents take a large number of medications, with cardiovascular, analgesic, and central nervous system agents being the most frequently prescribed.

    SUGGESTED READINGS
    1.
     Dharmarajan TS, Tota R. Appropriate prescribing of medications in older adults. Fam Pract Recert 2000;22:29-38.

    2. Leipzig RM. Pharmacology and appropriate prescribing. In: Cobbs EL, Duthie EH, Murphy JB, editors. Geriatrics review syllabus, 4th ed. Dubuque (IA): Kendall/Hunt Publishing Co; 1999:30-5.

    3. Schwartz JB. Clinical pharmacology. In: Hazzard WR, Blass JP, Ettinger WH, et al, editors. Principles of geriatric medicine and gerontology. 4th ed. New York: McGraw-Hill, Health Professions Division; 1999:303-31.

Click here to return to the questions

 


Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 1/04/08 • kkj