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Self-Assessment Questions


Answer 5
  1. Rendu-Osler-Weber syndrome. Also known as hereditary hemorrhagic telangiectasia, this is an autosomal dominant disorder that manifests as cutaneous and mucosal telangiectasias. Gastrointestinal bleeding is common and typically manifests in young people. Hereditary pancreatitis is not associated with telangiectasia. Celiac sprue can cause anemia but is not associated with cutaneous and mucosal telangiectasias. Sporadic angiectasia can cause bleeding but usually are seen in older individuals without cutaneous manifestations. Klippel-Trénaunay-Weber syndrome manifests as lower extremity nevi and varicose veins with rectal or vaginal hemangiomas or varices.

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