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Family Medicine
Hypothyroidism: Review Questions
Thomas F. Heston, MD, FAAFP
Dr. Heston is a physician in Family Medicine and nuclear medicine,
Kellogg, ID, and Online Education Coordinator, University of Health Sciences Antigua,
Dow Hill, Antigua.
Choose the single best answer for each question.
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1. Which of the following can cause myxedema coma?
- Advanced progression of hypothyroidism
- End-stage Graves disease
- Overdose of propylthiouracil
- Uncontrolled diabetes
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2. Which of the following is the most common cause of hypothyroidism?
- Acute thyroiditis
- Hashimotos disease
- Radioactive iodine exposure
- Thyroidectomy
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3. A patient has a normal serum thyrotropin (TSH) level, but a low thyroxine (T4)
level. What is the most appropriate diagnosis and treatment?
- Euthyroid sick syndrome; no treatment necessary
- Hyperthyroidism; administer Lugols solution
- Pituitary dysfunction; delay treatment until further work-up has been completed
- Primary hypothyroidism; administer levothyroxine
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4. Which of the following is the most common cause of goiter?
- Iodine deficiency
- Iodine excess
- Kwashiorkor
- Marasmus
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5. Which of the following is the best therapy for hypothyroidism?
- Dessicated thyroid
- Levothyroxine
- Liothyronine
- Liotrix
- Methimazole
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6. What is the recommended dosage of levothyroxine in elderly adults with stable primary hypothyroidism?
- Initial dose of 25 µg daily, titrated every 4 to 6 weeks to achieve a normal
serum TSH level
- Initial dose of 50 µg daily, titrated every 2 weeks to achieve a normal serum TSH level
- Initial dose of 75 µg daily, titrated every 2 weeks until the TSH level is suppressed below 0.1 mU/L
- Initial dose of 100 µg daily, titrated every 2 months to achieve a normal T4 level
- Initial dose of 100 µg daily, titrated every 4 weeks to achieve a normal T4 level
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7. Which of the following is NOT a clinical symptom of hypothyroidism?
- Cold intolerance
- Depression
- Diarrhea
- Muscle cramps
- Weight gain
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