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Self-Assessment Questions


General Endocrine Disorders: Review Questions

Catherine Anastasopoulou, MD

Dr. Anastasopoulou is an endocrinologist in private practice, affiliated with Albert Einstein Medical Center and Pennsylvania Hospital, Philadelphia, PA

Choose the single best answer for each question.

1. Which of the following is the most specific test to diagnose acromegaly?
  1. Magnetic resonance imaging of the pituitary gland
  2. Measurement of growth hormone (GH) levels during an oral glucose tolerance test
  3. Measurement of insulin-like growth factor I serum levels
  4. Measurement of random GH blood levels
  5. An octreotide scan
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2. A 35-year-old woman with amenorrhea is found to have an enlarged pituitary gland. Her prolactin level is 80 ng/L (normal, less than 20 ng/L), and her thyrotropin level is 100 µU/mL (normal, 0.5 to 4.5 µU/mL). Which of the following is the best treatment option for this patient?

  1. Administration of bromocriptine
  2. Administration of L-thyroxine
  3. Irradiation of the pituitary gland
  4. Resection of the pituitary gland
  5. Use of oral contraceptives
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3. All of the following are considered part of multiple endocrine neoplasia type 2 syndrome EXCEPT:

  1. Hyperparathyroidism
  2. Medullary thyroid carcinoma
  3. CMucosal neuromas
  4. Pheochromocytoma
  5. Prolactinoma
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  4. A previously healthy 45-year-old man is hospitalized in the intensive care unit for almost a month, following a car accident that caused serious head trauma. During evaluation of the patient for tachycardia, he was found to have a thyrotropin level of 0.3 µU/mL (normal, 0.5 to 4.5 µU/mL) and a serum thyroxine level of 1.2 µg/dL (normal, 5 to 12 µg/dL). What is the most likely diagnosis for this patient?
  1. Central hypothyroidism
  2. Euthyroid sick syndrome
  3. Hyperthyroidism
  4. Pituitary apoplexy
  5. Primary hypothyroidism
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5. Which of the following is the most common presentation of primary hyperparathyroidism?

  1. Asymptomatic hypercalcemia
  2. Bone fracture
  3. Kidney stones
  4. Osteoporosis
  5. Renal failure
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6. Which of the following is NOT a cause of hypertriglyceridemia?

  1. Acromegaly
  2. Alcoholism
  3. Diabetes mellitus
  4. Estrogen therapy
  5. Hypothyroidism
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