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Endocrinology


Answer 1
  1. Primary hyperparathyroidism. Compared with this patient’s high serum calcium level, her intact parathyroid hormone level (PTH intact) is inappropriately high.1 Primary hyperparathyroidism presents with hypercalcemia and a high PTH intact level. Hyperthyroidism, lung cancer, medications, and sarcoidosis all are associated with low or suppressed PTH intact levels.

    REFERENCE
    1. Kearns AE, Thompson GB. Medical and surgical management of hyperparathyroidism [published erratum appears in Mayo Clin Proc 2002;77:298]. Mayo Clin Proc 2002;77:87-91.
    2. Orwoll ES. Osteoporosis in men. Endocrinol Metab Clin North Am 1998;27:349-67.
    3. Delmas PD, Meunier PJ. The management of Paget’s disease of bone. N Engl J Med 1997;336:558-66.

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