Excessive growth hormone secretion causes fluid retention in different tissues of the body. After surgery, there is a sudden drop in growth hormone, resulting in self-limited diuresis.2 No other electrolytic abnormalities are related to this situation, and there is usually no problem in the posterior pituitary; therefore, diabetes insipidus should not be expected. If there was a problem with hyperglycemia, the urine specific gravity would be elevated.
- Diuresis caused by the decrease in growth hormone circulation.
2. Colao A, Ferone D, Marzullo P, et al. Systemic complications of acromegaly: epidemiology, pathogenesis and management. Endocrine Rev 2004;25:102-52.
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