Oral TMP-SMX is the appropriate treatment for a well-appearing patient with CA-MRSA. CA-MRSA isolates have high rates of susceptibility to TMP-SMX, rifampin, vancomycin, and linezolid.7,8 Many isolates of CA-MRSA are resistant to fluoroquinolones and erythromycin; thus, these antibiotics are not recommended to treat CA-MRSA infection. In most areas, clindamycin and doxycycline are potential treatment options. It is important for clinicians to be aware of local organism susceptibility patterns to appropriately treat MRSA infection.
- TMP-SMX orally.
7. convened Experts’ Meeting on Management of MRSA in the Community. Strategies for clinical management of MRSA in the community: summary of an experts’ meeting convened by the Centers for Disease Control and Prevention. 2006. Available at www.cdc.gov/ncidod/dhqp/pdf/ar/CAMRSA_ExpMtgStrategies.pdf. Accessed 28 Nov 2007.
8. Abrahamian FM, Shroff SD. Use of routine wound cultures to evaluate cutaneous abscesses for community-associated methicillin-resistant Staphylococcus aureus. Ann Emerg Med 2007;50:66–7.
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