Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Review of Clinical Signs Review Questions

Answer 1
  1. Nonclassic CAH. Symptoms of nonclassic CAH include premature pubarche, primary amenorrhea, menstrual dysfunction, hirsutism, acne, and infertility. CAH is the result of 21-hydroxylase deficiency, and laboratory testing that reveals an elevated 17-hydroxyprogesterone level (a result of the enzyme defect) is diagnostic of this condition. Thus, laboratory assessment is critical in diagnosing CAH. Asherman’s syndrome is characterized by secondary amenorrhea caused by intrauterine adhesions (also called “uterine synechiae”), but it would not be associated with laboratory abnormalities. Cushing’s syndrome would manifest with additional findings such as rapid weight gain, hypertension, and abdominal striae. PCOS would not manifest with elevated 17-hydroxyprogesterone levels but would certainly be included on the list of differential diagnoses.

Click here to return to the questions

Click here to read more about Signs of Hyperandrogenism in Women (Requires Adobe Acrobat Reader)

Review of Clinical Signs main page

Check our archives to test your knowledge in other clinical signs:

Review of Clinical Signs Archives

If you do not already have Acrobat Reader, simply click on the icon below, scroll down to the "Get the Free Acrobat Reader" heading and follow the instructions to install the program. Acrobat enables you to convert any document into an Adobe Portable Document Format (PDF) file for easy viewing.

Download Adobe Acrobat Reader


Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 10/24/08 • nvf