Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map
Review of Clinical Signs Review Questions

Answer 1
  1. Primary biliary cirrhosis. This patient’s elevated alkaline phosphatase is consistent with cholestasis, the predominant manifestation of primary biliary cirrhosis. Patients with this disease also may present with pruritus. Primary biliary cirrhosis has a 9:1 female to male ratio, making it more likely than primary sclerosing cholangitis. The patient denies a history of alcohol use, and results of liver function tests are not consistent with that of alcoholic cirrhosis (also known as Laennec’s cirrhosis) (eg, 2:1 ratio of aspartate aminotransferase/alanine aminotransferase). Nonalcoholic steatohepatitis is not likely to present with cholestasis.

Click here to return to the questions

Click here to read more about Pruritus: A Sign of Underlying Disease
(Requires Adobe Acrobat Reader)

Review of Clinical Signs main page

Check our archives to test your knowledge in other clinical signs:

Review of Clinical Signs Archives

If you do not already have Acrobat Reader, simply click on the icon below, scroll down to the "Get the Free Acrobat Reader" heading and follow the instructions to install the program. Acrobat enables you to convert any document into an Adobe Portable Document Format (PDF) file for easy viewing.

Download Adobe Acrobat Reader


Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 1/04/08 • kkj