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Review
of Clinical Signs

Heberden’s Nodes

Series Editor and Author: Frank L. Urbano, MD

1. Which of the following disorders has NOT been observed in connection with Heberden’s nodes?
  1. Gout
  2. Osteoarthritis
  3. Rheumatoid arthritis
  4. Systemic lupus erythematosus
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2. Which of the following statements concerning osteoarthritis is NOT true?

  1. It is solely caused by the degeneration of structures within the joints
  2. It is the most common type of arthritis
  3. It may cause effusions in larger joints
  4. Physical examination of affected joints typically reveals crepitus
  5. Symptoms may include joint pain and morning stiffness
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  3. Which of the following statements correctly describes the utility of Heberden’s nodes in the diagnosis of osteoarthritis?
  1. Heberden’s nodes are a poorer marker of generalized osteoarthritis than are distal interphalangeal (DIP) osteophytes
  2. Heberden’s nodes have a higher specificity than do immature DIP osteophytes as indicators of generalized osteoarthritis
  3. Heberden’s nodes have a positive predictive value of approximately 75% as indicators of osteoarthritis of other joints
  4. Heberden’s nodes have a sensitivity of approximately 66% for indicating generalized osteoarthritis
  5. There is good correlation between the presence of Heberden’s nodes and the presence of DIP osteophytes
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