Marfan Syndrome Umamahesh C. Rangasetty, MD, and Bernard M. Karnath, MD
	Choose the single best answer for each question. 1. A 30-year-old man who recently moved to the United States from Mexico presents with complains of palpitations and chest pain of 3 months’ duration. Palpitations are present throughout the day and increase at night. Chest pain is retrosternal and related to exertion and relieved by rest. Family history is significant for sudden death of both his father and grandfather in their forties. Physical examination is notable for a blood pressure of 140/30 mm Hg, collapsing pulse, and displaced apical impulse with an early diastolic murmur best heard along the right parasternal border in the third intercostal space. What is the most likely diagnosis? Bicuspid aortic valve Marfan syndrome Rheumatic heart disease Syphilis Takayasu’s arteritis Click here to compare your answer. 2. All of the following cause tall stature EXCEPT Chondrodysplasia Familial tall stature Homocystinuria Marfan syndrome Multiple endocrine neoplasia type IIB Click here to compare your answer.		3. All of the following are major signs of Marfan syndrome EXCEPT Aortic root dilatation Aortic dissection Pectus excavatum Dural ectasia Ectopia lentis Click here to compare your answer. 4. A 26-year-old woman presents to an ophthalmologist with a painful red eye. On examination, she is found to have elevated intraocular pressure with ectopia lentis. The lens is shifted upward and laterally. Which of the following evaluations would be most helpful in establishing a diagnosis of Marfan syndrome? Abdominal computed axial tomography (CAT) scan Echocardiography Serum lysine Serum methionine Slit-lamp eye examination Click here to compare your answer. 5. All of the following cause ectopia lentis EXCEPT Congenital contracture arachnodactyly Familial ectopia lentis syndrome Homocystinuria Marfan syndrome MASS syndrome Click here to compare your answer.
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