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Pediatric Rounds Review Questions
An 18-Month-Old Boy with Progressive Hoarseness

Answer 4

  1. CO2 laser treatment. Although multiple methods of treatment have been tested, and many adjuvant therapies are in ongoing clinical trials, no single modality or combination of modalities has been consistently shown to eradicate RRP HPV or guarantee long-term remission. However, microscopic CO2 laser excision has been the standard therapy in most cases of RRP. Procedures using “microdebrider” or “shaver” instruments may help reduce scarring and are becoming more popular. a-Interferon is sometimes used as an adjuvant treatment. Cidofovir may slow the rate of regrowth of RRP, but experience with this agent is limited. Currently there is no role for photodynamic therapy in the treatment of RRP.

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