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Pediatric Rounds Review Questions
An 18-Month-Old Boy with Progressive Hoarseness

Answer 3

  1. HPV 6, HPV 11. Papilloma viruses are classed by species specificity and by genetic homology; there are nearly 100 types, many of which have not been studied. HPV types 6 and 11 are most closely associated with RRP, and generally are not associated with malignancies; however, RRP can undergo malignant degeneration. HPV types 16 and 18 have been associated with malignancies of the aerodigestive tract and the cervix. HPV types 31 and 33 are between HPV 6/11 and 16/18 in malignant potential.

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