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JCOM Abstract


J Clin Outcomes Manage 
2008 Sep;15(9):443-449
A young woman with a thyroid nodule
Veloski C, Siraj ES

Abstract Objective: To review the diagnosis and treatment of patients with thyroid nodules. Methods: Review of the literature. Results: Thyroid nodules are common, with up to 7% of the adult population having palpable nodules. The primary aim in investigating a thyroid nodule is to exclude the possibility of malignancy, which occurs in about 5% of nodules. Evaluation of nodules includes a thorough history and physical examination, serum thyroid-stimulating hormone measurement, ultrasound, and, in some cases, fine-needle aspiration biop-sy. Surgical intervention is indicated in cytologically ma-lignant nodules or in cases suspicious for malignancy. In addition to surgical treatment, radioactive iodine ablation and suppressive treatment with levo-thyroxine are used to optimally manage thyroid cancer. Conclusion: Clinical decision making depends on proper evaluation of the tyroid nodule. Only a small percentage require surgical management.

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