|
 |
J Clin Outcomes Manage
2011 Nov;18(11):515-525
Recognition and management of bipolar depression
Schroeder E, Gao Y, Roberts J, El-Mallakh RS
Abstract: Objective: To review identification and treatment of bipolar depression. Methods: Literature review. Results: Bipolar depression is a common mood state in patients with both bipolar I and II disorders. Identification of bipolar depression depends on screening for both mania and hypomania. While it seems clear that treatment should generally minimize the use of antidepressants, there is a dearth of alternatives demonstrated to be both effective and safe. Avoidance of agents that increase synaptic serotonin appears to be a reasonable goal. While use of second-generation antipsychotic agents has increased, their utility may be more in reducing associated anxiety. Conclusions: Identification and treatment of bipolar depression remains challenging with an inadequate database to properly guide treatment decisions.
Clinical Review Article
Search the Turner White index to find abstracts of articles published in JCOM.
|
