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JCOM Abstract

J Clin Outcomes Manage 
2010 Nov;17(11):505-509
Improving patient adherence to warfarin therapy
Cruess DG, O'Leary K, Platt AB, Kimmel SE

Abstract Objective: To present an overview of factors that impact warfarin adherence. Methods: Review of the literature. Results: Warfarin is an anticoagulant medication commonly prescribed to prevent blood clots and thus reduce risk of stroke and venous thromboembolism. Although warfarin is highly effective in clinical trials, outcomes are optimized if patients are adherent and remain within a very narrow therapeutic range. This clinical review highlights some of the main factors that impact adherence to warfarin. Specifically, we identify a number of psychosocial factors that may act as potential barriers to warfarin adherence and discuss ways to modify these factors. Conclusion: There are a number of factors that impact whether or not patients are adherent to warfarin therapy. Identifying these factors can lead to the development of interventions to enhance adherence and perhaps promote improved health outcomes.

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