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JCOM Abstract


J Clin Outcomes Manage 
2006 Nov;13(11):628-646
Pharmacologic management of alcohol use disorders in the primary care setting
Paidisetty S Gordon AJ

Abstract Objective: To examine the rationale and evidence to support pharmacotherapies to treat alcohol problems in the primary care setting. Methods: Qualitative review of the literature. Results: Problem alcohol consumption is a prevalent problem in the United States and results in significant morbidity and mortality. In recent years, new pharmacologic treatments have been approved by the U.S. Food and Drug Administration to help health care providers treat patients with alcohol problems. The available research has shown that disulfiram, naltrexone, and acamprosate are effective for treating patients with alcohol problems. Certain patient characteristics promote enhanced outcomes for each medication. Whether combinations of pharmacotherapies or combinations of pharmacotherapy with nonpharmacotherapy enhance outcomes for problem drinkers are active research topics. Conclusion: Primary care providers should strongly consider the use of pharmacologic treatment as an adjunct to nonpharmacologic therapy to help patients reduce or eliminate alcohol consumption.

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