J Clin Outcomes Manage
Management of nonvariceal upper gastrointestinal bleeding
Zuberi SA, Targownik LE
Abstract Objective: To provide an overview of management of nonvariceal upper gastrointestinal bleeding (NVUGIB). Methods: Literature review in the context of a clinical case. Results: NVUGIB is a common condition, with approximately 30% to 50% of cases attributable to peptic ulcer disease. Endoscopy is the cornerstone of management. Comprehensive evidence-based guidelines exist to direct appropriate care for persons with NVUGIB. Adherence to these guidelines will promote the delivery of the most cost-effective care, allowing high-risk patients to receive appropriate management to reduce the risk of rebleeding and its complications and allow low-risk patients to be managed in the outpatient setting. Conclusion: Improvements in medical and endoscopic management have led to a decrease in the morbidity and mortality associated with gastrointestinal bleeding. It is hoped that further research will help better differentiate low-risk and high-risk patients and that further improvements in endoscopic techniques and post-endoscopic medical therapy may lead to a further reduction in rebleeding rates and mortality.
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