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JCOM Abstract


J Clin Outcomes Manage 
2004 Jun;11(6):385-395
Current challenges in the management of urinary tract infection
Nicolle LE

OBJECTIVE: To review the management of patients with and at risk for urinary tract infection (UTI). METHODS: Qualitative assessment of the literature. RESULTS: UTI is a common bacterial infection in adults. It presents as acute infection in otherwise well women or as complicated infection in individuals with functional or structural abnormalities of the genitourinary tract and in men. Management of UTI requires an understanding of characteristic features of presentation, laboratory diagnosis, natural history, and outcomes of therapy in different patient populations. Clinicians need to have knowledge of appropriate use of urine culture, approaches to empiric antimicrobial treatment, and population-specific factors that affect the duration of antimicrobial therapy, likelihood of recurrence, need for genitourinary investigations, and management of recurrent infection. Patients should not be screened for asymptomatic bacteriuria, except for pregnant women and individuals who are to undergo invasive procedures of the genitourinary tract with a high probability of mucosal bleeding. CONCLUSION: Understanding relevant differences in distinct populations is key to successful management of UTI.

Review, CME

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