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JCOM Abstract


J Clin Outcomes Manage 
2012 Jul;19(7):311-327
Management of stable COPD: focus on pharmacotherapy
Hatipoglu U, Aboussouan L

Abstract Objective: To review contemporary concepts and agents used in pharmacotherapy for chronic obstructive pulmonary disease (COPD). Methods: Qualitative assessment of recent trials with emphasis on impact of pharmacotherapy on clinical outcome measures. Results: Pharmacotherapy for COPD has become multifaceted to reflect the pathogenesis of the condition. Long-acting anti-muscarinic agents, long-acting ?2-agonists, inhaled corticosteroids in combination with long-acting ?2-agonists, phosphodiesterase inhibitors, and mucolytics have been associated with improved outcomes. Combination therapies incorporating different classes of medications hold promise for altering disease progression. Conclusion: Pharmacotherapy holds promise in significantly altering disease progression in COPD in addition to providing symptom relief.

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