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JCOM Abstract


J Clin Outcomes Manage 
2005 Jul;12(7):367-376
Medical management of systemic lupus erythematosus
Kamen DL, Gilkeson GS

Program Audience Primary care physicians. Educational Needs Addressed Systemic lupus erythematosus is a potentially severe, frequently disabling autoimmune disease with multiorgan involvement and a typically waxing and waning course. Early diagnosis can be difficult because of the insidious onset of predominantly nonspecific constitutional symptoms and highly variable clinical presentation. It is important for physicians to monitor and treat disease activity as well as advise avoidance of potential disease triggers. Patients need to stay up-to-date with routine health maintenance, including screening and prevention of osteoporosis, cardiovascular risk factor management, age-appropriate immunizations, and prompt treatment of infections due to the propensity for life-threatening complications of these comorbidities. Educational Objectives 1. Appreciate the wide variation in clinical presentation and course of systemic lupus erythematosus (SLE) 2. Know the potential complications of SLE and the leading causes of morbidity and mortality 3. Understand the role of laboratory testing in helping to make a diagnosis of SLE 4.Discuss the current pharmacologic options for SLE and their potential adverse effects

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