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JCOM Abstract

J Clin Outcomes Manage 
2011 Aug;18(8):347-350
Systemic inflammatory response syndrome at admission not associated with coronary artery disease severity in patients with NSTEMI
Yazigi F, Nazeri A, Kolluru A, Hagglund K, Saravolatz L, Lalonde T

Abstract: Objective: To examine the relationship between systemic inflammatory response syndrome SIRS on admission and the severity and extent of coronary artery disease (CAD) in patients with non-ST elevation myocardial infarction (NSTEMI). Methods: We conducted a retrospective chart review of patients with a discharge diagnosis of NSTEMI. Chart data were used to determine whether criteria for SIRS was present on admission. CAD severity was based on visual estimation during angiography. Results: There was no association between positive SIRS on admission and severity of CAD in NSTEMI patients (P = 0.193). However, we did find an association between a high percentage of neutrophils and CAD severity group (P = 0.033). Conclusion: Further study of the association of SIRS and extent of CAD in a larger sample is recommended.

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