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J Clin Outcomes Manage
2008 Aug;15(8):402-411
Barrett's esophagus: evaluation and management
Kamat PP, Anandasabapathy S
Educational Needs Addressed Barrett’s esophagus (BE) is a precancerous condition of the distal esophagus associated with the development of esophageal adenocarcinoma. BE predominantly affects a Western population, especially older Caucasian men, although incidence rates are rising among women and minorities. While age (> 40 years), chronic gastroesophageal reflux, and male gender have been identified as risk factors for development of BE, studies are increasingly exploring the association between obesity and the molecular basis for pathogenesis of BE. The increasing incidence of esophageal adenocarcinoma in recent years has sparked great interest in developing novel diagnostic modalities and therapeutic interventions in the management of BE. Additionally, there is a growing body of literature evaluating the cost-effectiveness of such modalities. Educational Objectives After participating in this CME activity, primary care physicians should be able to 1. Describe the epidemiology of BE 2. Describe endoscopic and pathologic findings in BE 3. Review the role of antireflux therapy in BE 4. Discuss the relationship between BE and obesity 5. Review therapeutic interventions used in the management of BE
Case-Based Review, CME
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