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Clinical Review Quiz

Neuroendocrine Tumors

Douglas G. Adler, MD

Dr. Adler is an assistant professor of medicine and director of Therapeutic Endoscopy, University of Utah School of Medicine/Huntsman Cancer Center, Salt Lake City, UT.

The questions below are based on the article
“Neuroendocrine Tumors: Review and Clinical Update”.

Choose the single best answer for each question.

1. Which of the following is the most common neuroendocrine tumor encountered in clinical practice?
  1. Carcinoid tumor
  2. Gastrinoma
  3. Glucagonoma
  4. Insulinoma
  5. Vasoactive intestinal peptide-producing tumors (VIPoma)
Click here to compare your answer.

2. In general, in a patient with a suspected neuroendocrine tumor, which imaging test should be obtained first?

  1. Abdominal ultrasound
  2. Computed tomography (CT) scan of the abdomen and pelvis
  3. Magnetic resonance imaging (MRI) of the abdomen and pelvis
  4. Positron emission tomography (PET) scan
  5. Somatostatin receptor scintigraphy (SRS)
Click here to compare your answer.

3. A patient with recurrent bleeding gastric and duodenal ulcers despite the use of high-dose acid suppression therapy is found to have a pancreatic mass on CT. This lesion is most likely secreting which of the following substances?

  1. Gastrin
  2. Glucagon
  3. Insulin
  4. Thyroxine
  5. Vasoactive intestinal peptide
Click here to compare your answer.

4. A 45-year-old woman has clinical signs and symptoms and laboratory findings consistent with the presence of a functioning carcinoid tumor. A CT scan of the patient’s abdomen and pelvis is unrevealing. Which of the following is the next best imaging test to identify the location of the primary lesion?

  1. Endoscopic ultrasound
  2. MRI of the abdomen and pelvis
  3. PET of the abdomen and pelvis
  4. Right upper quadrant ultrasound
  5. SRS
Click here to compare your answer .

5. What percentage of patients with multiple endocrine neoplasia type 1 (MEN1) who undergo complete resection of neuroendocrine tumors will develop a recurrence within 10 years?

  1. 1%
  2. 10%
  3. 25%
  4. 50%
  5. 75%
Click here to compare your answer.

6. MEN1 is most frequently associated with the development of which of the following enteropancreatic tumors?

  1. Gastrinoma
  2. Glucagonoma
  3. Insulinoma
  4. Somatostatinoma
  5. VIPoma
Click here to compare your answer.

7. Which of the following is the drug of choice to control symptoms in most patients with neuroendocrine tumors?

  1. Acid suppression therapy
  2. Insulin
  3. Interferon
  4. Intravenous glucose
  5. Somatostatin analogues
Click here to compare your answer.


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