Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Interactive:
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Quiz
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Exams
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map


Clinical Review Quiz

HIV Lipodystrophy Syndrome

Olumuyiwa Omolayo, MD

Dr. Omolayo is a hospitalist physician, Marshfield Clinic, Wausau, WI.



The questions below are based on the article
“HIV Lipodystrophy Syndrome”.


Choose the single best answer for each question.


1. Which of the following is not a complication comprising HIV lipodystrophy syndrome?
  1. Dyslipidemia
  2. Hypertension
  3. Insulin resistance
  4. Lipoatrophy
  5. Lipohypertrophy
Click here to compare your answer.


2. Which antiretroviral drug class is most commonly associated with development of lipoatrophy and lactic acidosis?

  1. Fusion inhibitor
  2. Integrase inhibitor
  3. Nonnucleoside reverse transcriptase inhibitor
  4. Nucleoside reverse transcriptase inhibitor
  5. Protease inhibitor
Click here to compare your answer.


3. A 45-year-old man with HIV infection on PI-based antiretroviral therapy presents for routine follow-up. His low-density lipoprotein cholesterol level has increased from a pretreatment value of 84 mg/dL to 178 mg/dL. Treatment with a statin is indicated, but the patient is concerned about drug interactions. Which of the following statins is not metabolized by the cytochrome P450 isoenzyme CYP3A4 and can be safely used in this patient?

  1. Atorvastatin
  2. Lovastatin
  3. Pravastatin
  4. Simvastatin
Click here to compare your answer.


4. All of the following are risk factors for the development of lactic acidosis EXCEPT
  1. Advanced immunosuppression
  2. Age older than 40 years
  3. Male gender
  4. Stavudine use
Click here to compare your answer.


5. According to the findings of the Data Collection on Adverse Events of Anti-HIV Drugs Study Group, what is the relative increase in the rate of myocardial infarction per year of exposure to antiretroviral therapy during the first 4 to 6 years?

  1. 6%
  2. 16%
  3. 26%
  4. 36%
Click here to compare your answer.


6. All of the following are helpful in making a diagnosis of body fat changes associated with HIV lipodystrophy syndrome EXCEPT

  1. Anthropometric measurements
  2. Bioelectrical impedance analysis
  3. Dual energy x-ray absorptiometry
  4. Magnetic resonance imaging
  5. Technetium bone scan
Click here to compare your answer.


7. All of the following are potential management strategies for lipohypertrophy EXCEPT

  1. Antiretroviral substitution to a non-PI-based regimen
  2. Exercise
  3. Metformin
  4. Recombinant human growth hormone
  5. Rosiglitazone
Click here to compare your answer.


 

Click here to read more about HIV Lipodystrophy Syndrome
(Requires Adobe Acrobat Reader)






Check our archives to test your knowledge in other featured articles:

Clinical Review Quiz Archive



If you do not already have Acrobat Reader, simply click on the icon below, scroll down to the "Get the Free Acrobat Reader" heading and follow the instructions to install the program. Acrobat enables you to convert any document into an Adobe Portable Document Format (PDF) file for easy viewing.

Download Adobe Acrobat Reader


 

Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 5/23/08 • nvf