Turner White CommunicationsAbout TWCSubscribeContact TWCHomeSearch
Hospital PhysicianJCOMSMPBRMsCart
Current Contents
Past Issue Archives
Self-Assessment Questions
Review of
Clinical Signs
Clinical Review
Pediatric Rounds
Resident Grand Rounds
Article Archives
Case Reports
Clinical Practice
Pediatric Rounds
Resident Grand Rounds
Review of
Clinical Signs

Guide to Reading
Hospital Physician
Editorial Board
Information for Authors

Reprints, Permissions, & Copyright
Site Map

Clinical Review Quiz

Multiple Myeloma

Darren S. Fentress, MD, Luisa A. Orrico, MD, Megan Kruspe, BS, Kristi S. Briscoe, BS, and Damian A. Laber, MD, FACP

Drs. Fentress and Orrico are resident physicians, Department of Medicine, University of Louisville; Ms. Kruspe and Ms. Briscoe are medical students, University of Louisville School of Medicine; and Dr. Laber is director of the Hematology and Medical Oncology Fellowship Program, University of Louisville, Louisville, KY.

The questions below are based on the article
“Multiple Myeloma”.

Choose the single best answer for each question.

1. What evaluations should be included in the initial work-up for suspected multiple myeloma (MM)?
  1. Serum protein electrophoresis, urine protein electrophoresis, and skeletal survey
  2. Complete blood count and complete metabolic profile
  3. Computed tomography scan of the chest, abdomen, and pelvis
  4. Technetium bone scan
  5. A and B
Click here to compare your answer.

2. On average, what percentage of patients with monoclonal gammopathy of unknown significance will progress to malignancy every year?

  1. 0%
  2. 1%
  3. 5%
  4. 10%
Click here to compare your answer.

3. What is the recommended management approach for a 57-year-old woman with newly diagnosed MM who has a beta-2 microglobulin level of 3.9 µg/mL, normal albumin, no end-organ damage, and no comorbidities?

  1. Start induction chemotherapy followed by high-dose chemotherapy with hematopoietic stem-cell rescue
  2. Active surveillance with treatment if progression occurs
  3. Melphalan and corticosteroid
  4. Thalidomide alone or with corticosteroid
Click here to compare your answer.

4. What is the best first-line treatment for a very active 68-year-old man with progressive, symptomatic MM and no comorbidities?
  1. Start induction chemotherapy followed by high-dose chemotherapy with hematopoietic stem-cell rescue
  2. Melphalan and corticosteroid
  3. Active surveillance with treatment only if progression occurs
  4. All are equal
Click here to compare your answer.

5. Management of MM in a patient with suspected cord compression must include

  1. Bone scan
  2. Dexamethasone and intravenous bisphosphonate therapy
  3. Urgent magnetic resonance imaging, dexamethasone, and neurosurgical consultation
  4. Careful observation
Click here to compare your answer.

6. Which statement is true regarding kidney disease in patients with MM?

  1. Renal disease is rare in patients with MM
  2. Myeloma kidney can present as acute renal failure
  3. Uric acid nephropathy is commonly associated with MM
  4. None of the above
Click here to compare your answer.


Click here to read more about Multiple Myeloma
(Requires Adobe Acrobat Reader)

Check our archives to test your knowledge in other featured articles:

Clinical Review Quiz Archive

If you do not already have Acrobat Reader, simply click on the icon below, scroll down to the "Get the Free Acrobat Reader" heading and follow the instructions to install the program. Acrobat enables you to convert any document into an Adobe Portable Document Format (PDF) file for easy viewing.

Download Adobe Acrobat Reader


Hospital Physician     JCOM     Seminars in Medical Practice
Hospital Physician Board Review Manuals
About TWC    Subscribe    Contact TWC    Home    Search   Site Map

Copyright © 2009, Turner White Communications
Updated 1/04/08 • kkj