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Peripheral Arterial Disease:
Diagnosis and Medical Management
Wendy S. Tzou, MD, and Emile R. Mohler, III, MD
Dr. Tzou is a cardiovascular medicine fellow, and Dr. Mohler is an associate professor of medicine and director of vascular medicine; both are in the Vascular Medicine Section, Cardiovascular Medicine Division, University of Pennsylvania, Philadelphia, PA.
The questions below are based on the article Peripheral Arterial Disease:
Diagnosis and Medical Management.
Choose the single best answer for each question.
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1. Which of the following conditions commonly underlies lower extremity peripheral arterial disease (PAD)?
- Aneurysm
- Arterial dissection
- Diffuse atherosclerosis
- Hypercoagulable state
- Thromboembolism
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2. Approximately how many Americans have PAD?
- 200,000
- 750,000
- 1 million
- 8 million
- 11 million
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3. Which of the following is the most common cause of mortality among patients with PAD?
- Myocardial infarction
- Postsurgical complications
- Pulmonary embolism
- Stroke
- Wound infection with sepsis
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4. Which of the following exemplifies the most common clinical presentation of PAD?
- A 55-year-old male smoker with dyslipidemia and reproducible cramping of the legs when walking up stairs that is relieved with rest
- A 60-year-old man with hypertension and
erectile dysfunction
- A 67-year-old woman with rheumatoid arthritis, stable angina, and complaints of cool feet
- A 75-year-old woman with type 2 diabetes mellitus, painful neuropathy, and chronic nonspecific muscle and joint aches
- An 80-year-old woman with multiple previous strokes with chronically slow-healing leg wounds
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5. Combined with a suggestive history and physical examination, which of the following tests is most effective in diagnosing and following the progression of PAD?
- Ankle-brachial pressure index at rest
- Magnetic resonance angiography
- Rose questionnaire administration
- Segmental pressures and pulse-volume recordings
- Treadmill walk test
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6. Which of the following therapies for PAD has been proven to reduce incident cardiovascular disease events?
- Aspirin
- Exercise rehabilitation therapy
- Insulin
- Pentoxifylline
- Smoking cessation
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