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Clinical Review Quiz

Peripheral Arterial Disease:
Diagnosis and Medical Management

Wendy S. Tzou, MD, and Emile R. Mohler, III, MD

Dr. Tzou is a cardiovascular medicine fellow, and Dr. Mohler is an associate professor of medicine and director of vascular medicine;
both are in the Vascular Medicine Section, Cardiovascular Medicine Division, University of Pennsylvania, Philadelphia, PA.

The questions below are based on the article
“Peripheral Arterial Disease: Diagnosis and Medical Management”.

Choose the single best answer for each question.

1. Which of the following conditions commonly underlies lower extremity peripheral arterial disease (PAD)?
  1. Aneurysm
  2. Arterial dissection
  3. Diffuse atherosclerosis
  4. Hypercoagulable state
  5. Thromboembolism
Click here to compare your answer.

2. Approximately how many Americans have PAD?

  1. 200,000
  2. 750,000
  3. 1 million
  4. 8 million
  5. 11 million
Click here to compare your answer.

3.  Which of the following is the most common cause of mortality among patients with PAD?

  1. Myocardial infarction
  2. Postsurgical complications
  3. Pulmonary embolism
  4. Stroke
  5. Wound infection with sepsis
Click here to compare your answer.

4. Which of the following exemplifies the most common clinical presentation of PAD?
  1. A 55-year-old male smoker with dyslipidemia and reproducible cramping of the legs when walking up stairs that is relieved with rest
  2. A 60-year-old man with hypertension and erectile dysfunction
  3. A 67-year-old woman with rheumatoid arthritis, stable angina, and complaints of cool feet
  4. A 75-year-old woman with type 2 diabetes mellitus, painful neuropathy, and chronic nonspecific muscle and joint aches
  5. An 80-year-old woman with multiple previous strokes with chronically slow-healing leg wounds
Click here to compare your answer.

5. Combined with a suggestive history and physical examination, which of the following tests is most effective in diagnosing and following the progression of PAD?

  1. Ankle-brachial pressure index at rest
  2. Magnetic resonance angiography
  3. Rose questionnaire administration
  4. Segmental pressures and pulse-volume recordings
  5. Treadmill walk test
Click here to compare your answer.

6. Which of the following therapies for PAD has been proven to reduce incident cardiovascular disease events?

  1. Aspirin
  2. Exercise rehabilitation therapy
  3. Insulin
  4. Pentoxifylline
  5. Smoking cessation
Click here to compare your answer.


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