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Review Questions: Perioperative Use of ß-Blocker Therapy in Patients Undergoing Noncardiac Surgery
Archana Roy, MD, and
J. Norman Patton, MD
Dr. Roy is a senior associate consultant, Division of Hospital Medicine, and Dr. Patton is chair, Division of Cardiology, Mayo Clinic, Jacksonville, FL.
The questions below are based on the article Perioperative Use of ß-Blocker Therapy in Patients Undergoing Noncardiac Surgery.
Choose the single best answer for each question.
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1. Perioperative use of ß-blocker therapy is indicated in all of the following patients except:
- A 75-year-old man with a history of coronary artery disease (CAD) and uncontrolled hypertension who is undergoing exploratory laparotomy for abdominal mass
- A 55-year-old man with well-controlled hypertension who is scheduled for nephrectomy for renal mass
- A 72-year-old man with a history of paroxysmal atrial fibrillation who is scheduled for hip arthroplasty
- An 85-year-old woman with type 2 diabetes mellitus on insulin who is scheduled for elective gall bladder surgery
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2. An 85-year-old man with a history of CAD, uncontrolled hypertension, and type 2 diabetes for which he takes insulin is scheduled for carotid endarterectomy. Dobutamine stress echocardiogram shows a fixed myocardial perfusion defect with a left ventricular ejection fraction (LVEF) of 35%. The patientıs medications include labetalol 100 mg twice a day, lisinopril 20 mg/d, and atorvastatin 40 mg/d. What changes should be made to optimize this patientıs medical management to reduce perioperative cardiac mortality and morbidity?
- Add metoprolol or atenolol preoperatively
- Discontinue labetalol and start atenolol
preoperatively
- Discontinue labetalol and start metoprolol
preoperatively
- Continue labetalol and make no changes
- Continue labetalol and adjust dose to control blood pressure and to achieve a heart rate less than 70 bpm
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3. A 72-year-old woman with a history of mild to moderate chronic obstructive pulmonary disease (COPD), CAD, and paroxysmal atrial fibrillation is scheduled for resection of a colonic mass suspicious for malignancy. What step should be taken to reduce perioperative cardiac complications?
- Start low-dose atenolol or metoprolol by mouth preoperatively
- Start diltiazem for prevention of postoperative atrial fibrillation
- Do not give ß-blocker therapy as it is contraindicated in a patient with COPD
- Do not use prophylactic treatment as the patientıs medical condition is stable
- Do not recommend surgery as patient is high risk for surgery
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4. A 65-year-old man with history of peripheral vascular disease is undergoing emergency exploratory laparotomy for perforated bowel. The patientıs medical history is significant for CAD and congestive heart failure with a LVEF of 40%. He underwent a coronary artery bypass grafting procedure 5 years ago and has had frequent angina for the last 3 months. Physical examination shows a blood pressure of 160/90 mm Hg and a heart rate of 94 bpm. What is the next step in preoperative medical management of this patient?
- Give atenolol or metoprolol by mouth preoperatively and titrate to achieve a heart rate less than 70 bpm
- Give atenolol or metoprolol intravenously preoperatively and titrate to achieve heart rate less than 70 bpm
- Give calcium channel blocker for blood pressure control
- Give angiotensin-converting enzyme inhibitor for better control of blood pressure
- Patient requires emergency surgery; recommend to proceed with surgery without further treatment
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5. The patient in question 4 has tolerated the surgical procedure well. What adjustments should be made to his ß-blocker regimen postoperatively?
- ß-Blockers are not needed postoperatively;
discontinue immediately
- Discontinue ß-blocker after 5 days
- Discontinue ß-blocker 48 hours after surgery
- Continue intravenous ß-blocker postoperatively until discharge
- Continue ß-blocker postoperatively for 30 days and change to oral when appropriate
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6. A 72-year-old woman with severe, steroid-dependent COPD requires surgery for a fractured hip. Her medical history is significant for CAD and compensated congestive heart failure. An electrocardiogram shows first-degree heart block. What is appropriate treatment for her preoperatively?
- Start metoprolol 12.5 mg orally twice a day
- Start metorpolol 25 mg orally twice a day and optimize for heart rate control
- Start atenolol 5 mg intravenously 30 minutes prior to surgery
- Do not start ß-blocker as patient has severe COPD
- Do not start ß-blocker as patient has first-degree heart block
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