Part 1: Ischemic Stroke: Pathophysiology and Principles of Localization

Matthew Brandon Maas, MD, and Joseph E. Safdieh, MD

Dr. Maas is a fellow in Stroke and Neurocritical Care, Harvard Medical School, Departments of Neurology, Massachusetts General and Brigham and Women’s Hospitals, Boston, MA. Dr. Safdieh is an assistant professor of neurology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY.

Question 9

Research on Susac’s syndrome indicates a pathologic role of antiendothelial cell antibodies. Several autoimmune conditions can lead to cerebral infarction. A pathologic self-recognizing antibody has been identified for which of the following presumably autoimmune stroke-causing conditions?

  •  Behçet’s disease
  •  Giant cell arteritis
  •  Primary angiitis of the CNS
  •  Sneddon’s syndrome
  •  Wegener’s granulomatosis

Updated 1/12/2010 • mcf | Copyright ©2013 Turner White Communications