Part 4: Venous Thromboembolism
Elisabeth M. Battinelli, MD, PhD
Assistant Professor of Medicine, Harvard Medical School, Associate Physician, Division of Hematology, Brigham and Women's Hospital, Boston, MA
Jean M. Connors, MD
Assistant Professor of Medicine, Harvard Medical School, Medical Director, Anticoagulation Management Service, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA
A 44-year-old man arrives in clinic to discuss his risk of developing a thrombotic event. His mother, age 76, was recently diagnosed with antiphospholipid syndrome after suffering a PE and testing positive for lupus anticoagulant on 2 separate occasions 3 months apart. His mother is currently on anticoagulation and the patient is worried that he also has a risk of developing a thrombotic event because of his family history. During the visit, it is noted that the patient is obese (body mass index [BMI] ≥30) and leads a sedentary lifestyle.
What should the physician tell the patient regarding his risk of having a thrombotic event in the future?